DeepTech refers to technologies rooted in scientific discoveries and engineering breakthroughs and it is increasingly seen as the foundation for solving humanity’s toughest problems. From climate resilience and quantum computing to advanced healthcare and space exploration, the promise of DeepTech extends far beyond incremental innovation. But building DeepTech startups is notoriously hard: they require long development cycles, heavy capital investment, and multidisciplinary expertise.
This is where Singapore is quietly taking center stage. Over the last decade, the city-state has positioned itself as one of Asia’s most compelling hubs for DeepTech innovation, not through chance but through a deliberate embrace of venture building. By pairing research talent with structured startup creation, Singapore is charting a path that could make it a global leader in translating science into scalable businesses.
The DeepTech Imperative
DeepTech is not just hype. According to Boston Consulting Group, DeepTech startups globally attracted more than US$60 billion in funding in 2023, double the levels seen in 2016. Yet the barriers to entry remain high. Unlike software startups, where a minimum viable product can be built in weeks, DeepTech ventures often require years of research before commercial viability.
Singapore has recognized both the challenge and the opportunity. With limited natural resources, the country has long invested in knowledge as its most strategic asset. Today, that strategy is paying off as its universities and research institutions - such as the National University of Singapore (NUS) and A-STAR - are increasingly integrated into venture-building pipelines.
A Government-Backed Ecosystem
The Singapore government has been one of the most active global backers of DeepTech venture building. Through initiatives like the SGInnovate Deep Tech Nexus Strategy, launched in 2017, the country committed more than US$150 million to support the translation of science into companies. SGInnovate itself has directly invested in over 100 DeepTech startups spanning fields like autonomous robotics, medtech, and agritech.
This model is designed not just to fund startups but to systematically derisk them. By offering labs, pilot facilities, and structured venture building programs, Singapore reduces the “valley of death” between academic research and commercial application.
Case Study: A-STAR Spinouts
One of the best examples of Singapore’s DeepTech venture building comes from A-STAR, the Agency for Science, Technology and Research. Over the past five years, A-STAR has spun out dozens of startups in biotech, advanced materials, and AI. Companies like Nanoveu, which develops nanotechnology-based films for optics and antiviral protection, have scaled regionally thanks to early support from A-STAR’s venture co-creation efforts.
Another case is RWDC Industries, a biodegradable plastics startup that originated in Singapore and has since raised more than US$135 million in growth funding. RWDC’s success underscores how research-driven ventures can become globally relevant with the right support structure.
Temasek and the Long-Term View
DeepTech requires patient capital, and few institutions embody patience better than Singapore’s sovereign wealth fund, Temasek. Through its venture-building arm Xora Innovation, Temasek partners with scientists and entrepreneurs at the very earliest stages, often before a commercial application is fully proven.
This long-term approach is critical. Traditional VCs often shy away from DeepTech because of long timelines, but venture studios like Xora de-risk the process by building operational capacity around founders. This allows breakthroughs in quantum computing or synthetic biology to be pursued without the pressure of unrealistic short-term returns.
Singapore as Asia’s Testbed
Another advantage lies in Singapore’s role as a testbed for emerging technologies. With its compact size, advanced infrastructure, and supportive regulators, the city-state often serves as a “living laboratory” for pilots.
For example, autonomous vehicle trials, drone delivery pilots, and next-gen biotech therapies have all been deployed in Singapore earlier than in most regional markets. This testbed status makes the country an attractive base for DeepTech venture builders: startups can validate complex technologies locally before scaling across Asia’s 650 million-strong Southeast Asian market.
Talent at the Core
DeepTech thrives on talent density, and Singapore has invested heavily in building a global research workforce. The country attracts scientists and engineers through initiatives like the Research, Innovation and Enterprise (RIE) 2025 Plan, which allocated US$25 billion to science and innovation over five years.
What sets Singapore apart is how this talent is integrated into venture building. Instead of leaving researchers isolated in academia, programs connect them with entrepreneurs, operators, and investors who can help translate breakthroughs into market-ready companies. This culture of collaboration is one reason why Singapore consistently ranks among the top 10 in the Global Innovation Index.
Looking Forward: Singapore’s DeepTech Ambition
The next decade will determine whether Singapore’s DeepTech bets pay off. The foundations are strong: government backing, venture studios, sovereign wealth participation, and global research talent. The challenge lies in scaling beyond local pilots into global leaders.
If Singapore’s studios can consistently produce DeepTech unicorns - companies solving real-world problems in energy, healthcare, and materials - it will cement its place not just as Asia’s DeepTech hub but as one of the world’s great innovation ecosystems.
For founders, Singapore offers a rare combination: scientific depth, supportive policy, and venture-building structures that reduce the odds of failure. For investors, it provides a gateway to high-potential DeepTech startups in Asia with the added security of government and sovereign fund alignment.
The message is clear: while Silicon Valley may dominate software, the next generation of world-changing science-driven startups could well be born in Singapore’s venture studios.